HOW WE AGE IS AFFECTED BY OUR GENETICS AND EPIGENETICS
All life has one thing in common: it begins with a cell. While lifespan is the number of years we live, our healthspan represents the number of years in which we are in a state of good health and free of disease. Longevity research shows the age-related decline of two crucial endogenous molecules – coenzyme NAD+ and antioxidant CoQ10. Your body’s natural concentrations of NAD+ and CoQ10 begin depleting due to ageing, fatigue, strenuous exercise and illness. Ageing is a series of interconnected processes that are known scientifically as the 12 Hallmarks of Ageing.
There is a hierarchical relationship between the 12 interconnected characteristics of ageing. Primary characteristics trigger harmful triggers, the effects of which increase with age. The antagonistic markers are initially beneficial in response to damage, but become increasingly problematic over time. Finally, the integrative hallmarks reflect our body's inability to cope with the cumulative damage from the primary and antagonistic hallmarks of ageing. This leads to a loss of tissue homeostasis; in other words, our cells become compromised and our tissues have a hard time repairing themselves.
CLINICAL RESEARCH
We collaborate with top academic research institutions to test our carefully crafted longevity formulations. With plant-specific research, we uncover new health benefits and endpoints, pushing forward advancements in longevity science. We founded LongevitylifeLabs to develop novel applications of microbioms to enhance biodiversity and recover ecosystems.
TELOMERES: THE CLOCK WITHIN OUR CELLS
We inherit telomeres, protective caps on our chromosomes, from our parents. However, everyone's telomeres shorten with age. This shortening is a major contributor to age-related cellular breakdown. When telomeres become too short, cells can no longer reproduce, leading to tissue degeneration and ultimately, cell death. Cells in the skin, hair, and immune system are particularly susceptible due to their frequent replication.
Microorganisms, from the Greek - ¨mikros¨= small organisms. They are therefore fully-fledged independent beings that are integrated into the networks of life, just like humans themselves. They are a wide range of entities that physically exist but are generally not visible to the human eye. The respective quality of the microscope defines whether we regard them as physically existing or not.
In the 1990s, Japanese scientists began to differentiate the various hierarchical functions and levels of microorganisms and to select those microorganisms that are able to make a targeted contribution to the harmonisation and productivity of the processes in their environment. We call them the CEOs and designers of production processes.
